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treatment with dmso  (MedChemExpress)


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    MedChemExpress treatment with dmso
    Treatment With Dmso, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 575 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/treatment+with+dmso/Dimethyl+sulfoxide/pm42048041-113-6-9
    Average 99 stars, based on 575 article reviews
    treatment with dmso - by Bioz Stars, 2026-10
    99/100 stars

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    Related Articles

    Mouse Assay:

    Article Title: Combined Inhibition of PI3K and STAT3 Signaling is Effective in Bladder Cancer Treatment
    Article Snippet: .. Mice were randomized into 2 groups (n = 2) for treatment with DMSO (as a control), (10 mg/kg) copanlisib (MCE BAY 80-6946) i.p. every 3 days. ..

    Control:

    Article Title: Combined Inhibition of PI3K and STAT3 Signaling is Effective in Bladder Cancer Treatment
    Article Snippet: .. Mice were randomized into 2 groups (n = 2) for treatment with DMSO (as a control), (10 mg/kg) copanlisib (MCE BAY 80-6946) i.p. every 3 days. ..

    Article Title: Combined Inhibition of PI3K and STAT3 signaling effectively inhibits bladder cancer growth
    Article Snippet: Briefly, Male C57BL/6 J mice (6 weeks old) were given drinking water containing 0.05% (w/v) BBN (TCI, catalog no. B0938) for 20 weeks. .. After the BBN administration, mice were given normal drinking water and were randomized into 4 groups (n = 11) for treatment with DMSO (as a control), (10 mg/kg) copanlisib (MCE BAY 80-6946), (4 mg/kg) napabucasin (MCE BBI608), or both drugs (10 mg/kg copanlisib and 4 mg/kg napabucasin) i.p. every 3 days. ..

    Article Title: Combined Inhibition of PI3K and STAT3 signaling effectively inhibits bladder cancer growth.
    Article Snippet: Briefly, Male C57BL/6 J mice (6 weeks old) were given drinking water containing 0.05% (w/v) BBN (TCI, catalog no. B0938) for 20 weeks. .. After the BBN administration, mice were given normal drinking water and were randomized into 4 groups (n= 11) for treatment with DMSO (as a control), (10 mg/kg) copanlisib (MCE BAY 80-6946), (4 mg/kg) napabucasin (MCE BBI608), or both drugs (10 mg/kg copanlisib and 4mg/kg napabucasin) i.p. every 3 days. ..

    Thermal Shift Assay:

    Article Title: Squalene attenuates doxorubicin resistance in hepatocellular carcinoma by targeting SIRT6 to inhibit ERK1 deacetylation.
    Article Snippet: .. Cellular thermal shift assay (CETSA) After treatment with DMSO (MCE, USA) or squalene (MCE, USA) for 24 h, cells were washed with PBS containing protease inhibitors (Beyotime, China) three times. .. Cell pellets were resuspended, injected into PCR tubes, and heated in a thermal cycler (Bio-Rad, USA) from 44 °C to 60 °C for 4 min for denaturation.

    other:

    Article Title: Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
    Article Snippet: Perioperative neurocognitive disorders (PND) are common complications in elderly surgical patients, yet the molecular mechanisms underlying this condition remain poorly understood.. Accumulating evidence suggests that HDAC7—a member of the class IIa histone deacetylase (HDAC) family—plays a crucial role in brain injury and can activate the NF-κB pathway independently of its deacetylase activity.. In the present study, we investigated whether upregulation of hippocampal HDAC7 contributes to PND through NF-κB–mediated mitochondrial dysfunction and ferroptosis.



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    Transcriptome sequencing analysis of C. albicans treated <t>with</t> <t>BD11</t> . (A) Volcano plots display comparisons of C. albicans ATCC 10231 treated with <t>DMSO</t> or BD11 (6.25 µg/mL) for 8h. The two vertical dashed lines in the graph indicate the 2-fold expression difference threshold and the horizontal dashed line represents the P -value threshold of 0.05. Red dots indicate up-regulated genes, blue dots indicate down-regulated genes, and grey dots represent genes with no significant difference in expression. (B) The most significantly enriched 20 GO terms for DEGs. Circle size represents the gene number. The FDR (false discovery rate, corrected P -value) generally ranges from 0 to 1, with values closer to zero indicating more significant enrichment. (C) Top 30 KEGG pathways for DEGs. The horizontal axis represents the pathway name, and the vertical axis represents the −log 10 of the P -value for each pathway's enrichment. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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    Transcriptome sequencing analysis of C. albicans treated <t>with</t> <t>BD11</t> . (A) Volcano plots display comparisons of C. albicans ATCC 10231 treated with <t>DMSO</t> or BD11 (6.25 µg/mL) for 8h. The two vertical dashed lines in the graph indicate the 2-fold expression difference threshold and the horizontal dashed line represents the P -value threshold of 0.05. Red dots indicate up-regulated genes, blue dots indicate down-regulated genes, and grey dots represent genes with no significant difference in expression. (B) The most significantly enriched 20 GO terms for DEGs. Circle size represents the gene number. The FDR (false discovery rate, corrected P -value) generally ranges from 0 to 1, with values closer to zero indicating more significant enrichment. (C) Top 30 KEGG pathways for DEGs. The horizontal axis represents the pathway name, and the vertical axis represents the −log 10 of the P -value for each pathway's enrichment. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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    Transcriptome sequencing analysis of C. albicans treated <t>with</t> <t>BD11</t> . (A) Volcano plots display comparisons of C. albicans ATCC 10231 treated with <t>DMSO</t> or BD11 (6.25 µg/mL) for 8h. The two vertical dashed lines in the graph indicate the 2-fold expression difference threshold and the horizontal dashed line represents the P -value threshold of 0.05. Red dots indicate up-regulated genes, blue dots indicate down-regulated genes, and grey dots represent genes with no significant difference in expression. (B) The most significantly enriched 20 GO terms for DEGs. Circle size represents the gene number. The FDR (false discovery rate, corrected P -value) generally ranges from 0 to 1, with values closer to zero indicating more significant enrichment. (C) Top 30 KEGG pathways for DEGs. The horizontal axis represents the pathway name, and the vertical axis represents the −log 10 of the P -value for each pathway's enrichment. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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    Image Search Results


    Transcriptome sequencing analysis of C. albicans treated with BD11 . (A) Volcano plots display comparisons of C. albicans ATCC 10231 treated with DMSO or BD11 (6.25 µg/mL) for 8h. The two vertical dashed lines in the graph indicate the 2-fold expression difference threshold and the horizontal dashed line represents the P -value threshold of 0.05. Red dots indicate up-regulated genes, blue dots indicate down-regulated genes, and grey dots represent genes with no significant difference in expression. (B) The most significantly enriched 20 GO terms for DEGs. Circle size represents the gene number. The FDR (false discovery rate, corrected P -value) generally ranges from 0 to 1, with values closer to zero indicating more significant enrichment. (C) Top 30 KEGG pathways for DEGs. The horizontal axis represents the pathway name, and the vertical axis represents the −log 10 of the P -value for each pathway's enrichment. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Journal: Journal of Advanced Research

    Article Title: Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism

    doi: 10.1016/j.jare.2025.07.044

    Figure Lengend Snippet: Transcriptome sequencing analysis of C. albicans treated with BD11 . (A) Volcano plots display comparisons of C. albicans ATCC 10231 treated with DMSO or BD11 (6.25 µg/mL) for 8h. The two vertical dashed lines in the graph indicate the 2-fold expression difference threshold and the horizontal dashed line represents the P -value threshold of 0.05. Red dots indicate up-regulated genes, blue dots indicate down-regulated genes, and grey dots represent genes with no significant difference in expression. (B) The most significantly enriched 20 GO terms for DEGs. Circle size represents the gene number. The FDR (false discovery rate, corrected P -value) generally ranges from 0 to 1, with values closer to zero indicating more significant enrichment. (C) Top 30 KEGG pathways for DEGs. The horizontal axis represents the pathway name, and the vertical axis represents the −log 10 of the P -value for each pathway's enrichment. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Article Snippet: BD11 or DMSO treatment of C. albicans ATCC 10231 samples was performed as described in the electron microscopy methods section.

    Techniques: Sequencing, Expressing

    BD11 impairs cell wall integrity and perturbs energy metabolism in C. albicans . (A) Representative TEM images of C. albicans ATCC 10231 and BD11 -treated C. albicans ATCC 10231 (n = 3). Scale bar, 500 nm. The structures indicated by the arrows are mitochondria. (B) Calcofluor white staining of C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6 h (n = 3). (C) Intracellular ATP content in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6h (n = 4). (D) The intracellular SDH activity in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6h (n = 4). The data are shown as the mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 vs DMSO.

    Journal: Journal of Advanced Research

    Article Title: Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism

    doi: 10.1016/j.jare.2025.07.044

    Figure Lengend Snippet: BD11 impairs cell wall integrity and perturbs energy metabolism in C. albicans . (A) Representative TEM images of C. albicans ATCC 10231 and BD11 -treated C. albicans ATCC 10231 (n = 3). Scale bar, 500 nm. The structures indicated by the arrows are mitochondria. (B) Calcofluor white staining of C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6 h (n = 3). (C) Intracellular ATP content in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6h (n = 4). (D) The intracellular SDH activity in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 30 °C for 6h (n = 4). The data are shown as the mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 vs DMSO.

    Article Snippet: BD11 or DMSO treatment of C. albicans ATCC 10231 samples was performed as described in the electron microscopy methods section.

    Techniques: Staining, Activity Assay

    Compound BD11 inhibits C. albicans filamentation and biofilm formation. (A) Representative images of C. albicans ATCC 10231 were grown at 30 °C or 42°C for 6 h in the absence or presence of a gradient of BD11 (n = 3). (B) Representative images of C. albicans ATCC 10231 were grown at 42°C for 6 h or 12 h in the absence or presence of a gradient of BD11 (n = 3). (C–D) Biofilms formed by C. albicans ATCC 10231 (C) or C. albicans CMCC 98001 (D) were grown at 37 °C for 24 h in the absence or presence of BD11 as indicated. Crystal violet staining was used for the quantitative analysis of biofilms (n = 3). (E) Intracellular ATP content in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 42 °C for 6 h (n = 5). (F) qPCR analysis of mRNA levels of RAS1 (n = 4) , TPK2 (n = 3) and EFG1 (n = 3) in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 42 °C for 6 h. The data are shown as the mean ± SEM. * P < 0.05, ** P < 0.01, **** P < 0.0001 vs. DMSO. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Journal: Journal of Advanced Research

    Article Title: Boronic acid derivatives inhibit Candida albicans growth by compromising energy metabolism

    doi: 10.1016/j.jare.2025.07.044

    Figure Lengend Snippet: Compound BD11 inhibits C. albicans filamentation and biofilm formation. (A) Representative images of C. albicans ATCC 10231 were grown at 30 °C or 42°C for 6 h in the absence or presence of a gradient of BD11 (n = 3). (B) Representative images of C. albicans ATCC 10231 were grown at 42°C for 6 h or 12 h in the absence or presence of a gradient of BD11 (n = 3). (C–D) Biofilms formed by C. albicans ATCC 10231 (C) or C. albicans CMCC 98001 (D) were grown at 37 °C for 24 h in the absence or presence of BD11 as indicated. Crystal violet staining was used for the quantitative analysis of biofilms (n = 3). (E) Intracellular ATP content in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 42 °C for 6 h (n = 5). (F) qPCR analysis of mRNA levels of RAS1 (n = 4) , TPK2 (n = 3) and EFG1 (n = 3) in C. albicans ATCC 10231 treated with DMSO or BD11 (0.78, 1.56, and 3.125 µg/mL) at 42 °C for 6 h. The data are shown as the mean ± SEM. * P < 0.05, ** P < 0.01, **** P < 0.0001 vs. DMSO. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

    Article Snippet: BD11 or DMSO treatment of C. albicans ATCC 10231 samples was performed as described in the electron microscopy methods section.

    Techniques: Staining